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Thread: Spinal Cord Injury Articles Posted by Manouli

  1. #541
    kbailey post this already, but I post it here too to have it any time we want to see it again.

    I think this is great, because doctors try it on a human being and they can learn if it works or not. The guy said he got better in one month.

    Military Veteran with Spinal Cord Injury Is First Patient to Receive Intraspinal Injections of Reprogramed Stem Cell Therapy from Precision StemCell
    Within one month, paraplegic patient experiences movement

    Press Release: Precision StemCell – 7 hrs ago

    GULF SHORES, Ala., Jan 8, 2013 /PRNewswire/ -- In 2007, an ATV accident left military veteran Scott Williams with a spinal cord injury that paralyzed him from the upper chest down. In the summer of 2012, after undergoing an autologous adipose-derived stem cell transplant into his spine at the Precision StemCell ( facility in Gulf Shores, Williams began noticing increased sensation in his left leg and the ability to slightly move both feet.

    "Within one month, I was able to move my feet some, and I haven't done that in over five years," Williams stated. "I feel that this is amazing progress." Williams received the "Selegeline reprogramed adipose derived stem cells" treatment that Precision StemCell has been giving to patients suffering from amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease. Seventy-five percent of those ALS patients have experienced improvements in moving, breathing and speech.


  2. #542
    First Oral Drug for Spinal Cord Injury Improves Movement in Mice
    Jan. 8, 2013 — An experimental oral drug given to mice after a spinal cord injury was effective at improving limb movement after the injury, a new study shows.

    The compound efficiently crossed the blood-brain barrier, did not increase pain and showed no toxic effects to the animals.

    "This is a first to have a drug that can be taken orally to produce functional improvement with no toxicity in a rodent model," said Sung Ok Yoon, associate professor of molecular & cellular biochemistry at Ohio State University and lead author of the study. "So far, in the spinal cord injury field with rodent models, effective treatments have included more than one therapy, often involving invasive means. Here, with a single agent, we were able to obtain functional improvement."


  3. #543
    Reported January 9, 2013
    Medical First! New Hope for the Paralyzed

    MIAMI, Fla. (Ivanhoe Newswire) -- Confined to a wheelchair for life; that’s the fate of many of the 12 thousand people who suffer traumatic spinal cord injuries in the United States every year. Now, a one of a kind trial could change the face of spinal cord research forever.

    “Before I even hit the ground I knew I was paralyzed,” Marc Bouniconti told Ivanhoe.

    Marc Bouniconti’s final football play paralyzed him from the neck down.

    “Next thing I know, I went from the best shape of my life to fighting for my life in a split second,” Bouniconti said.

    Now, the son of an NFL hall of famer is fighting to walk again and this could be the key. For the first time the FDA has approved a trial to evaluate the safety of Schwann cells, cells responsible for sending electrical signals throughout the nervous system.

    Last edited by manouli; 01-09-2013 at 08:57 PM. Reason: more details

  4. #544
    Time-dependent changes in the microenvironment of injured spinal cord affects the therapeutic potential of neural stem cell transplantation for spinal cord injury.

    The transplantation of neural stem/progenitor cells (NS/PCs) at the sub-acute phase of spinal cord injury, but not at the chronic phase, can promote functional recovery.


  5. #545
    The Race To Cure Spinal Cord Injuries
    January 15, 2013 by: PropThink | includes: CUR, NVIV.OB, STEM

    By Jason Napodano, CFA

    A Big Opportunity - For Everyone

    Spinal Cord Injury ((SCI)) refers to an injury to the spinal cord that is caused by direct trauma or secondary damage to the surrounding bone, tissue, or blood vessels. Classification of the extent of the injury is based on neurological responses, touch and pinprick sensations tested in each dermatome (an area of the skin supplied by a single spinal nerve), and strength of ten key muscles on each side of the body, including the hip flexion (L2), shoulder shrug (C4), elbow flexion (C5), wrist extension (C6), and elbow extension (C7). The four categories of SCI classification and their respective percent of the market are: Complete Tetraplegia (16%), Incomplete Tetraplegia (41%), Complete Paraplegia (22%), and Incomplete Paraplegia (21%) (source).

    Incidence of spinal cord injury occurs at about 40 cases per 1 million persons. In the U.S., we estimate there are approximately 12,000 new cases per year. Include Canada and Western Europe and the total number of new cases per year is around 20,000. Adding in India, China, Australia, Latin America and Japan and the total grows to over 100,000 new (acute) cases of SCI worldwide per year. Prevalence of SCI in the U.S. is around 300,000 individuals between the U.S. and Canada. We estimate that 75% of these patients would benefit from a new treatment paradigm.


  6. #546


    This is great, even though is for acute paralysis, that is the best way to do human clinical trials to get the cure.

    Acorda Gets US Army Support – Analyst Blog
    By : nasdaq

    Acorda Therapeutics, Inc. ( ACOR ) recently
    announced that it has been awarded a research contract worth $2.67
    million by the US Army Medical Research and Material Command
    (USAMRMC). The research contract will support the development of

    The company plans to initiate a phase II trial evaluating the
    safety and tolerability of the candidate in patients suffering from
    acute spinal cord injury (SCI). Enrollment process for the study is
    expected to start in the first half of 2013.

    AC105 enjoys fast-track status in the U.S. for the improvement
    of functional recovery in acute SCI patients. Acorda intends to


  7. #547
    Spinal injury patients 'benefit from two surgeons'RSS Feed

    21 January 2013

    People who suffer severe spinal injuries and go under the knife in a bid to overcome their troubles could find that having two surgeons overseeing the procedure is significantly better than just one.

    New research carried out at the University of California, San Francisco (UCSF) has found that two heads is almost certainly preferable to one when it comes to carrying out medical operations and surgery. Indeed, patients are said to benefit from this in numerous ways during their stay in hospital.


  8. #548
    New Hope for Patients with Spinal Cord Injuries
    Publish date: Jan 28, 2013

    ROSEMONT, Ill., Jan. 28, 2013 /PRNewswire-USNewswire/ -- Currently there is no effective treatment used in clinical practice for patients with an injured spinal cord. However, a group of orthopaedic scientists have recently discovered that the administration of microRNA-210 could be an effective treatment for an injured spinal cord by promoting regeneration following injury.


    Previously, microRNA-210 has been studied as an effective treatment for cancer and other diseases. Scientists noted that there was an absence of this particular gene in cancerous tumors, but it was found in abundance in healthy tissue. By delivering what was missing directly to the diseased tumor, scientists were able to stop the progression of the disease. Other scientists, however, noted that microRNA has the possibility to actually promote the growth of certain cancers.

    Dr. Satoshi Ujigo from Hiroshima University in Japan and his colleagues applied this same theory to injured spinal cords hoping for similar results. His work was recently presented at the Orthopaedic Research Society's (ORS) 2013 Annual Meeting in San Antonio, Texas this January

    Last edited by manouli; 01-29-2013 at 02:51 PM.

  9. #549
    Senior Member
    Join Date
    Jul 2010

    Dr. Perez Research Evaluation?

    Quote Originally Posted by manouli View Post
    Zapping body and brain boosts movement in paralysed
    Updated 17:35 30 November 2012 by Jessica Hamzelou

    A single session of nerve stimulation has improved the movement of people with spinal cord injuries. Mimicking the passage of nerve signals by stimulating a muscle as well as the brain has boosted recovery and helped people to regain better control of their movements.

    Voluntary movement requires a signal from the brain, which is passed down the spinal cord and then to neurons in muscles. Damage to the spinal cord can interrupt this pathway, resulting in paralysis.

    To improve the control of movement in people with these injuries, Monica Perez and Karen Bunday at the University of Pittsburgh in Pennsylvania used electrical and magnetic stimulation to strengthen the connection between two nerves involved in voluntary movement of the index finger.

    We were contacted about participating in a research study for Dr. Perez at UPMC Pittsburgh. I don't want to get too excited, but I am hopeful that maybe this is the start of something good? For all of us? Wow. Anybody here ever participate in any of these types of studies? We have no idea what to expect . . .

  10. #550
    Senior Member muskie's Avatar
    Join Date
    Sep 2011
    Port Jervis, NY
    Quote Originally Posted by Nickib View Post
    We were contacted about participating in a research study for Dr. Perez at UPMC Pittsburgh. I don't want to get too excited, but I am hopeful that maybe this is the start of something good? For all of us? Wow. Anybody here ever participate in any of these types of studies? We have no idea what to expect . . .
    Please keep us updated, can you tell us your level of injury?
    Please join me and donate a dollar a day at and copy and paste this message to the bottom of your signature

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