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Thread: Spinal Cord Injury Articles Posted by Manouli

  1. #1061
    Nanoparticles promote functional healing following spinal cord injury
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    Science Highlights
    July 24, 2019
    Novel approach also shows promise for autoimmune diseases
    Paralyzing damage in spinal cord injury (SCI) is often caused by the zealous immune response to the injury. NIBIB-funded engineers have developed nanoparticles that lure immune cells away from the spinal cord, allowing regeneration that restored spinal cord function in mice.
    Just as in the brain, the spinal cord has a blood brain barrier that protects the delicate nerves from potential damage from various insults, including blocking immune cells from moving in to clean up debris from the injury.

    more....


    https://www.nibib.nih.gov/news-event...al-cord-injury

  2. #1062
    Senior Member NW-Will's Avatar
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    Thank you.

    For some reason the hyperlink isn't working on your post .. https://www.nibib.nih.gov/news-event...al-cord-injury
    Quote Originally Posted by manouli View Post
    Nanoparticles promote functional healing following spinal cord injury
    Share:
    Science Highlights
    July 24, 2019
    Novel approach also shows promise for autoimmune diseases
    Paralyzing damage in spinal cord injury (SCI) is often caused by the zealous immune response to the injury. NIBIB-funded engineers have developed nanoparticles that lure immune cells away from the spinal cord, allowing regeneration that restored spinal cord function in mice.
    Just as in the brain, the spinal cord has a blood brain barrier that protects the delicate nerves from potential damage from various insults, including blocking immune cells from moving in to clean up debris from the injury.

    more....


    https://www.nibib.nih.gov/news-event...al-cord-injury

  3. #1063

    Smile

    Quote Originally Posted by NW-Will View Post
    Thank you.

    For some reason the hyperlink isn't working on your post .. https://www.nibib.nih.gov/news-event...al-cord-injury
    Thank you! I don't know what did happen.

  4. #1064
    NEWS FEATURE
    31 July 2019
    How a revolutionary technique got people with spinal-cord injuries back on their feet
    Electrical stimulation has promised huge gains for people with paralysis. Now comes the hard part ? getting beyond those first steps.

    Rob Summers was flat on his back at a rehabilitation institute in Kentucky when he realized he could wiggle his big toe. Up, down, up, down. This was new ? something he hadn?t been able to do since a hit-and-run driver left him paralysed from the chest down. When that happened four years earlier, doctors had told him that he would never move his lower body again. Now he was part of a pioneering experiment to test the power of electrical stimulation in people with spinal-cord injuries.
    ?Susie, look, I can wiggle my toe,? Summers said.
    Susan Harkema, a neurophysiologist at the University of Louisville in Kentucky, sat nearby, absorbed in the data on her computer. She was incredulous. Summers?s toe might be moving, but he was not in control. Of that she was sure. Still, she decided to humour him. She asked him to close his eyes and move his right toe up, then down, and then up. She moved on to the left toe. He performed perfectly.
    more...
    https://www.nature.com/articles/d41586-019-02306-z

  5. #1065
    Senior Member
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    I can wiggle my toes on left anytime I want to right I really really have to concentrate but that's it nothing for 17 years

  6. #1066
    Quote Originally Posted by vjls View Post
    I can wiggle my toes on left anytime I want to right I really really have to concentrate but that's it nothing for 17 years
    mmm

  7. #1067
    ReNetX Bio Announces Initiation of Patient Dosing in the First Phase 1 Clinical Trial of Fusion Protein AXER-204





    August 14, 2019 09:02 ET | Source: ReNetx Bio


    NEW HAVEN, Conn., Aug. 14, 2019 (GLOBE NEWSWIRE) -- ReNetX Bio, Inc., a leading biotechnology company committed to reversing disease and damage for patients suffering from central nervous system (CNS) disorders, has announced a successful first patient dosing in a Phase 1 clinical trial of its lead drug candidate, fusion protein AXER-204.


    more...


    https://www.globenewswire.com/news-r...-AXER-204.html

  8. #1068
    Quote Originally Posted by manouli View Post
    ReNetX Bio Announces Initiation of Patient Dosing in the First Phase 1 Clinical Trial of Fusion Protein AXER-204





    August 14, 2019 09:02 ET | Source: ReNetx Bio


    NEW HAVEN, Conn., Aug. 14, 2019 (GLOBE NEWSWIRE) -- ReNetX Bio, Inc., a leading biotechnology company committed to reversing disease and damage for patients suffering from central nervous system (CNS) disorders, has announced a successful first patient dosing in a Phase 1 clinical trial of its lead drug candidate, fusion protein AXER-204.



    https://www.globenewswire.com/news-r...-AXER-204.html


    Watch: Spinal Cord Injury Research
    Larry Wong, Edmonton Journal
    Updated: August 15, 2019
    ShareAdjustCommentPrint
    Ana Lucas-Osma, a research associate at the University of Alberta?s Faculty of Rehabilitation Medicine, suffered a T7 spinal cord injury in Spain when she was 18.
    She was one of seven passengers in a school van that rolled down a hill and it left her in a wheelchair.
    The University of Alberta and the University of California, San Francisco are teaming up to launch the world?s first Open Data Commons for preclinical Spinal Cord Injury research (ODC-SCI).
    A consortium of international organizations will be providing $3.3 million CAD to help fund the initiative. The ODC-SCI will improve spinal cord injury research and treatment worldwide by reducing data bias and equipping scientists by making data more accessible.

    more...
    https://edmontonjournal.com/news/loc...njury-research

  9. #1069

    Animal studies of protein AXER-204?

    Quote Originally Posted by manouli View Post
    ReNetX Bio Announces Initiation of Patient Dosing in the First Phase 1 Clinical Trial of Fusion Protein AXER-204





    August 14, 2019 09:02 ET | Source: ReNetx Bio


    NEW HAVEN, Conn., Aug. 14, 2019 (GLOBE NEWSWIRE) -- ReNetX Bio, Inc., a leading biotechnology company committed to reversing disease and damage for patients suffering from central nervous system (CNS) disorders, has announced a successful first patient dosing in a Phase 1 clinical trial of its lead drug candidate, fusion protein AXER-204.


    more...


    https://www.globenewswire.com/news-r...-AXER-204.html



    Is anybody aware of animal studies of ReNetX Bio fusion protein AXER-204 prior to this Phase 1 trial?

    I've looked everywhere I can't find it ..... doesn't mean it doesn't exist I just can't find anything.

  10. #1070
    Quote Originally Posted by spayne View Post
    Is anybody aware of animal studies of ReNetX Bio fusion protein AXER-204 prior to this Phase 1 trial?

    I've looked everywhere I can't find it ..... doesn't mean it doesn't exist I just can't find anything.
    http://sci.rutgers.edu/forum/showthr...=1#post1878432

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