Spinal Cord Injury Articles Posted by Manouli

[manouli]

VirTrial Awarded FDA-Approved Decentralized Clinical Trial with Hope Biosciences
by VirTrial | Oct 9, 2019 | Press and News | 0 comments
Scottsdale, AZ (October 9, 2019) ? VirTrial has been awarded an FDA-approved hybrid decentralized clinical trial (DCT) with Hope Biosciences. The study provides Hope Biosciences? autologous, adipose-derived culture-expanded mesenchymal stem cells (HB-adMSC?s) for the treatment of spinal cord injury/disorder (SCI/D). Study protocol incorporates remote visits via VirTrial?s telehealth platform.
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https://virtrial.com/virtrial-awarde...e-biosciences/

$6.3 million DARPA grant boosts spinal repair research
Grant funds University collaboration with Intel, R.I. Hospital, Micro Leads Medical to create spinal tech
By Kathleen Meininger
Contributing Writer
Friday, October 11, 2019


Summer Zhang / Herald
A $6.3 million research grant from the U.S. Defense Advanced Research Projects Agency will allow University researchers to develop an implantable spinal device to help repair neural connections in the spine.
The grant will fund a University collaboration with the Rhode Island Hospital, Intel Corporation and Micro Leads Medical.
This new project falls at the intersection of neuroscience, computer science, engineering and clinical research. Researchers have created an implantable device that can record and stimulate areas both above and below a spinal injury in patients with spinal cord damage. Once the device records a signal traveling down the spinal cord from the brain, the signal is sent to a computer interface to be decoded by neural network algorithms, which are computer systems designed to recognize and transmit neural patterns. Then, the signal is used to stimulate the area of the spinal cord below the injury.
more...
http://www.browndailyherald.com/2019...pair-research/

[manouli]

$6.3 million DARPA grant boosts spinal repair research
Grant funds University collaboration with Intel, R.I. Hospital, Micro Leads Medical to create spinal tech
By Kathleen Meininger
Contributing Writer
Friday, October 11, 2019


Summer Zhang / Herald
A $6.3 million research grant from the U.S. Defense Advanced Research Projects Agency will allow University researchers to develop an implantable spinal device to help repair neural connections in the spine.
The grant will fund a University collaboration with the Rhode Island Hospital, Intel Corporation and Micro Leads Medical.
This new project falls at the intersection of neuroscience, computer science, engineering and clinical research. Researchers have created an implantable device that can record and stimulate areas both above and below a spinal injury in patients with spinal cord damage. Once the device records a signal traveling down the spinal cord from the brain, the signal is sent to a computer interface to be decoded by neural network algorithms, which are computer systems designed to recognize and transmit neural patterns. Then, the signal is used to stimulate the area of the spinal cord below the injury.
more...
http://www.browndailyherald.com/2019...pair-research/

Salk scientists receive NIH funding to map brain circuitry for movement
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Reviewed by Kate Anderton, B.Sc. (Editor)Oct 18 2019
A team of Salk scientists led by Professor Martyn Goulding has been awarded $14.3 million over five years by the National Institutes of Health (NIH) to create a high-resolution atlas of how the mouse brain generates and controls skilled forelimb movements, such as reaching and grasping. Knowledge generated by the grant will provide a better understanding of not only how the brain controls movement, but also how it is affected by neurological diseases and spinal cord injuries that compromise arm, wrist and hand function.
more...
https://www.news-medical.net/news/20...-movement.aspx

[manouli]

Salk scientists receive NIH funding to map brain circuitry for movement
Download PDF Copy
Reviewed by Kate Anderton, B.Sc. (Editor)Oct 18 2019
A team of Salk scientists led by Professor Martyn Goulding has been awarded $14.3 million over five years by the National Institutes of Health (NIH) to create a high-resolution atlas of how the mouse brain generates and controls skilled forelimb movements, such as reaching and grasping. Knowledge generated by the grant will provide a better understanding of not only how the brain controls movement, but also how it is affected by neurological diseases and spinal cord injuries that compromise arm, wrist and hand function.
more...
https://www.news-medical.net/news/20...-movement.aspx

just for the knowledge
Spinal Cord Stimulation Devices Market by Product, Application and Geography - World Forecast to 2023
Dublin, Oct. 21, 2019 (GLOBE NEWSWIRE) -- The "Global Spinal Cord Stimulation Devices Market (2019-2025)" report has been added to ResearchAndMarkets.com's offering.

The Global Spinal Cord Stimulation Devices Market size is expected to reach $2.8 billion by 2025, rising at a market growth of 8% CAGR during the forecast period.

The increased cases of the failed back syndrome and complex regional pain syndrome are expected to positively impact the growth of the market. Failed back syndrome is a chronic pain that occurs after spinal surgeries for leg pain or back pain. Post the surgery, the pain reduces or the condition worsens due to scar tissue that arises around the spinal nerve roots.

Spinal cord stimulation devices treat patients who previously failed to get positive results from spinal surgeries. The devices block the pain before it reaches the brain. Therefore, the increased rate of patients suffering from chronic pain after surgeries is expected to boost the demand for these devices over the forecast period. Additionally, technological developments are pushing the growth and developments in the market. For example, Medtronic's Intellis is the smallest implantable spinal cord stimulator that was created to overcome limitations with the existing systems.
read...
http://markets.financialcontent.com/...?GUID=39009371

[manouli]

just for the knowledge
Spinal Cord Stimulation Devices Market by Product, Application and Geography - World Forecast to 2023
Dublin, Oct. 21, 2019 (GLOBE NEWSWIRE) -- The "Global Spinal Cord Stimulation Devices Market (2019-2025)" report has been added to ResearchAndMarkets.com's offering.

The Global Spinal Cord Stimulation Devices Market size is expected to reach $2.8 billion by 2025, rising at a market growth of 8% CAGR during the forecast period.

The increased cases of the failed back syndrome and complex regional pain syndrome are expected to positively impact the growth of the market. Failed back syndrome is a chronic pain that occurs after spinal surgeries for leg pain or back pain. Post the surgery, the pain reduces or the condition worsens due to scar tissue that arises around the spinal nerve roots.

Spinal cord stimulation devices treat patients who previously failed to get positive results from spinal surgeries. The devices block the pain before it reaches the brain. Therefore, the increased rate of patients suffering from chronic pain after surgeries is expected to boost the demand for these devices over the forecast period. Additionally, technological developments are pushing the growth and developments in the market. For example, Medtronic's Intellis is the smallest implantable spinal cord stimulator that was created to overcome limitations with the existing systems.
read...
http://markets.financialcontent.com/...?GUID=39009371

Polymerized estrogen can protect nervous system cells and promote regeneration
Download PDF Copy
Reviewed by James Ives, M.Psych. (Editor)Oct 23 2019
Spinal cord damage that causes paralysis and reduced mobility doesn't always stop with the initial trauma, but there are few treatment options to halt increased deterioration -- and there is no cure. Researchers at Rensselaer Polytechnic Institute have developed a promising new biomaterial that could offer targeted treatment to the damaged spinal cord and tissue, preventing further damage.
In research published today in Nature Communications, an interdisciplinary team from Rensselaer demonstrated how estrogen -- a natural hormone produced in the body -- can be polymerized into a slow-releasing biomaterial and applied to nervous system cells to protect those cells and even promote regeneration.
read...
https://www.news-medical.net/news/20...eneration.aspx

[manouli]

Polymerized estrogen can protect nervous system cells and promote regeneration
Download PDF Copy
Reviewed by James Ives, M.Psych. (Editor)Oct 23 2019
Spinal cord damage that causes paralysis and reduced mobility doesn't always stop with the initial trauma, but there are few treatment options to halt increased deterioration -- and there is no cure. Researchers at Rensselaer Polytechnic Institute have developed a promising new biomaterial that could offer targeted treatment to the damaged spinal cord and tissue, preventing further damage.
In research published today in Nature Communications, an interdisciplinary team from Rensselaer demonstrated how estrogen -- a natural hormone produced in the body -- can be polymerized into a slow-releasing biomaterial and applied to nervous system cells to protect those cells and even promote regeneration.
read...
https://www.news-medical.net/news/20...eneration.aspx

[manouli]

Polymerized estrogen can protect nervous system cells and promote regeneration
Download PDF Copy
Reviewed by James Ives, M.Psych. (Editor)Oct 23 2019
Spinal cord damage that causes paralysis and reduced mobility doesn't always stop with the initial trauma, but there are few treatment options to halt increased deterioration -- and there is no cure. Researchers at Rensselaer Polytechnic Institute have developed a promising new biomaterial that could offer targeted treatment to the damaged spinal cord and tissue, preventing further damage.
In research published today in Nature Communications, an interdisciplinary team from Rensselaer demonstrated how estrogen -- a natural hormone produced in the body -- can be polymerized into a slow-releasing biomaterial and applied to nervous system cells to protect those cells and even promote regeneration.
read...
https://www.news-medical.net/news/20...eneration.aspx

A protein that pulls the brake on nerve growth
Date:
October 31, 2019
Source:
DZNE - German Center for Neurodegenerative Diseases
Summary:
During embryonic development, nerve cells form thin, long extensions, which they use to wire up a complex network, the brain. Scientists have now identified a protein that regulates the growth of these extensions by pulling a brake. In the long run, their findings could help to develop new approaches for the treatment of spinal cord injuries.
read...
https://www.sciencedaily.com/release...1031114746.htm

[manouli]

2,051 viewsOct 29, 2019, 08:47pm A New HBO Documentary, Starring Mountain Biker Paul Basagoitia, Brings Awareness To Spinal Cord Injuries /sites/sarahkim//sites/sarahkim/Sarah Kim Contributor Diversity & Inclusion I write about diversity and inclusion in the realm of disabilities.


At any time in life, someone can become a part of the disability community. Disability is the only minority group that doesn’t discriminate against anyone since it can become a part of a person’s identity spontaneously. Mountain biker Paul Basagoitia experienced this phenomenon first-hand back in 2015 when he crashed his bike after a 40-foot drop at the Red Bull Rampage and sustained a spinal cord injury, fracturing his 12th vertebrae. The injury left him paralyzed from the waist down.
read...
https://www.forbes.com/sites/sarahki.../#3c410d9b27e1

[manouli]

2,051 viewsOct 29, 2019, 08:47pm A New HBO Documentary, Starring Mountain Biker Paul Basagoitia, Brings Awareness To Spinal Cord Injuries /sites/sarahkim//sites/sarahkim/Sarah Kim Contributor Diversity & Inclusion I write about diversity and inclusion in the realm of disabilities.


At any time in life, someone can become a part of the disability community. Disability is the only minority group that doesn?t discriminate against anyone since it can become a part of a person?s identity spontaneously. Mountain biker Paul Basagoitia experienced this phenomenon first-hand back in 2015 when he crashed his bike after a 40-foot drop at the Red Bull Rampage and sustained a spinal cord injury, fracturing his 12th vertebrae. The injury left him paralyzed from the waist down.
read...
https://www.forbes.com/sites/sarahki.../#3c410d9b27e1

Researchers from the US have developed a biosensor that may help lead to safe stem cell therapies for treating Alzheimer?s and Parkinson?s diseases and other neurological disorders.
The device, created by a team from Rutgers University in New Jersey, features a unique graphene and gold-based platform and high-tech imaging and monitors the fate of stem cells by detecting genetic material (RNA) involved in turning such cells into brain cells (neurons).
Stem cells can become many different types of cells. As a result, stem cell therapy shows promise for regenerative treatment of neurological disorders such as Alzheimer?s, Parkinson?s, stroke and spinal cord injury, with diseased cells needing replacement or repair.
read...
https://eandt.theiet.org/content/art...-cell-therapy/

[manouli]

Researchers from the US have developed a biosensor that may help lead to safe stem cell therapies for treating Alzheimer?s and Parkinson?s diseases and other neurological disorders.
The device, created by a team from Rutgers University in New Jersey, features a unique graphene and gold-based platform and high-tech imaging and monitors the fate of stem cells by detecting genetic material (RNA) involved in turning such cells into brain cells (neurons).
Stem cells can become many different types of cells. As a result, stem cell therapy shows promise for regenerative treatment of neurological disorders such as Alzheimer?s, Parkinson?s, stroke and spinal cord injury, with diseased cells needing replacement or repair.
read...
https://eandt.theiet.org/content/art...-cell-therapy/

Woman Suffers Severe Spinal Cord Injury, Finds Relief at Danbury Hospital
Western Connecticut Health Network October 23, 2019



⦁ Katherine (Kathy) Wenning tripped and broke her neck when she was at her weekend home in Washington, Connecticut. Kathy and her husband, Michael Dennis, knew she needed emergency care. They weren?t sure where to go because they live in Manhattan, and they?ve never needed urgent medical attention while staying in Washington.
⦁ Kathy and Michael consulted with friends from New York who also spend time in Connecticut and they recommended Danbury Hospital.
⦁ Kathy had successful surgery to treat her severe spinal cord injury, followed by extensive occupational therapy and physical therapy.
⦁ Today, Kathy is fully functional and has been able to maintain her active lifestyle.
DANBURY, Connecticut, October 23, 2019 ? A freak accident left Katherine (Kathy) Wenning unable to move her upper body. She knew she needed medical attention, but she was at her country getaway in Washington, Connecticut ? two hours by car from her home in Manhattan and the New York medical system she trusted. Kathy put her faith in a neurosurgeon and care team at Danbury Hospital to treat her severe spinal cord injury.

more...
https://www.westernconnecticuthealth...-patient-story

[manouli]

Woman Suffers Severe Spinal Cord Injury, Finds Relief at Danbury Hospital
Western Connecticut Health Network October 23, 2019



⦁ Katherine (Kathy) Wenning tripped and broke her neck when she was at her weekend home in Washington, Connecticut. Kathy and her husband, Michael Dennis, knew she needed emergency care. They weren?t sure where to go because they live in Manhattan, and they?ve never needed urgent medical attention while staying in Washington.
⦁ Kathy and Michael consulted with friends from New York who also spend time in Connecticut and they recommended Danbury Hospital.
⦁ Kathy had successful surgery to treat her severe spinal cord injury, followed by extensive occupational therapy and physical therapy.
⦁ Today, Kathy is fully functional and has been able to maintain her active lifestyle.
DANBURY, Connecticut, October 23, 2019 ? A freak accident left Katherine (Kathy) Wenning unable to move her upper body. She knew she needed medical attention, but she was at her country getaway in Washington, Connecticut ? two hours by car from her home in Manhattan and the New York medical system she trusted. Kathy put her faith in a neurosurgeon and care team at Danbury Hospital to treat her severe spinal cord injury.

more...
https://www.westernconnecticuthealth...-patient-story

BioArctic's interim analysis of phase 1/2 study of SC0806 in patients with CSC injury halts spinal cord injury project
BioArctic AB (STO: BIOAB), a Swedish research-based biopharmaceutical company, reported on Monday the results of an interim analysis of a phase 1/2 study of SC0806 in patients with complete spinal cord injury.
Under this analysis, none of the patients showed an effect as measured by electrical impulses passing through the injured area after treatment. Electrical impulse passage is considered a prerequisite to restore motor function. This means that the study did not meet the primary efficacy endpoint. Also, the results did not show convincing efficacy on secondary endpoints regarding motor function, other functions or quality of life.
Based on these results BioArctic has decided to stop the inclusion of patients in the ongoing phase 1/2 study. The company has also decided not to further develop the complete spinal cord injury project after the final patient has completed the training programme.
more...
https://www.m2.com/m2/web/story.php/20199359700