Quote Originally Posted by manouli View Post
BioArctic's interim analysis of phase 1/2 study of SC0806 in patients with CSC injury halts spinal cord injury project
BioArctic AB (STO: BIOAB), a Swedish research-based biopharmaceutical company, reported on Monday the results of an interim analysis of a phase 1/2 study of SC0806 in patients with complete spinal cord injury.
Under this analysis, none of the patients showed an effect as measured by electrical impulses passing through the injured area after treatment. Electrical impulse passage is considered a prerequisite to restore motor function. This means that the study did not meet the primary efficacy endpoint. Also, the results did not show convincing efficacy on secondary endpoints regarding motor function, other functions or quality of life.
Based on these results BioArctic has decided to stop the inclusion of patients in the ongoing phase 1/2 study. The company has also decided not to further develop the complete spinal cord injury project after the final patient has completed the training programme.
Experimental Treatment Yields Amazing Results For Mayo Patient

Rochester, MN (KROC-AM News) - The Mayo Clinic cautions the human trial is still in a very early stage, but the first patient to receive a new stem cell therapy for paralysis has experienced an amazing recovery.
53-year-old Chris Barr suffered a catastrophic spinal cord injury in a surfing accident in 2017, and after intensive rehabilitation, faced a lifetime with limited movement and feeling below his neck. That apparently made him the perfect candidate for a Mayo Clinic study led by Dr. Mohamad Bydon, who enrolled Barr in a phase 1 clinical trial to determine if the experimental therapy is safe. It involves removing stem cells from fat tissue in the patient?s body and expanding their number into a mega-dose that is then injected into the injured spinal cord.
"We want to intervene when the physical function has plateaued, so that we do not allow the intervention to take credit for early improvements that occur as part of the natural history with many spinal cord injuries. In this case, the patient was injected with stem cells nearly one year after his injury," Dr. Bydon says.