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Thread: Wild East or scientific feast?

  1. #1

    Wild East or scientific feast?

    Stem cells in China
    Wild East or scientific feast?

    sorry this is from 2010 we should have results from those trials.

    In the field of stem cells, China is showing that it can do world-class science. It is a shame, then, that so many fraudsters operate and that officialdom turns a blind eye
    Jan 14th 2010 | Beijing | from the print edition

    This must be one of Dr. Young's trials.


    Dr Thorsteinsdottir found that though many hospitals are making a profit from offering unproven therapies, a number of proper clinical trials are also being conducted using stem cells, for conditions such as heart-muscle damage, ischemia (restricted blood supply) of the limbs, liver disease and neurological disorders. These include a multi-centre trial organised by the China Spinal Cord Injury Network, a consortium of over two dozen centres in mainland China, Hong Kong and Taiwan, to test whether a combination of lithium and transplants of stem cells from umbilical-cord blood could lead to improvements in patients with spinal-cord injury.


  2. #2
    Spinal Cord Injury Clinical Trials for Chronic Spinal Cord Injury

    Regeneration of long spinal tracts require overcoming of three obstacles. First, the injury site lacks markers to direct growing axons and is often filled with cysts that block axonal growth. Cell transplants "bridge" the injury site. Second, axons take many months and years to grow. Sustained growth factor support is needed. Third, several substances are known to stop axonal growth in the spinal cord, particularly a myelin-based protein called Nogo and chondoritin-6-sulfate-proteoglycans.

    The China Spinal Cord Injury Network (ChinaSCINet) and Spinal Cord Injury Network USA (SCINetUSA) are carrying out clinical trials to test therapies that address each of these obstacles. We discovered that the drug lithum strongly stimulate stem cells in umbilical cord blood and also neural stem cells in the spinal cord to grow and to produce growth factors. Therefore, our first set of clinical trials are testing the safety, feasibility, and efficacy of lithium treatment and transplantation of umbilical cord blood cells in people with chronic spinal cord injury.

    In particular, we have proposed the following clinical trials in ChinaSCINet:
    • Phase 0 Observation trial. These are trials that recruit subjects with chronic spinal cord injury and observe them for 6 months to a year. These trials establish the ability of the centers to recruit patients, examine them, and convince them to come back several times over 6-12 months.


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