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Thread: Paraplegic move legs after stem cell procedure- Brazilian Center of Cell Theraphy

  1. #1
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    Paraplegic move legs after stem cell procedure- Brazilian Center of Cell Theraphy

    I couldn't find this news in English. I'll try to translate a section of the today headline news from the Brazilian Center of Cell Therapy of Hospital Saint Rafael. This is one of the Brazilian top research centers.
    This English article is from last year and gives some details about the procedure when was done on animals http://www.cbtc-hsr.org/en/art.php?i...9kTGKxPm8GTk8=


    Paraplegic move legs after stem cell procedure

    A 47 year paraplegic legs and foot sensibility and movement came back after a experimental stem cell experiment. The treatment is based on the mesenchymal stem cells that are removed from the hip bone from the patient, separated and enriched in a solution of hormones and vitamins and implanted at the spinal cord.
    The first patient was a police men that is paraplegic for the last nine years after a fall that caused lumbar SCI. The patient started to fell his legs and foot six weeks after the stem cell procedure. And also started to control his bladder allowing him to stop Urinary Catheter Care.

    Portuguese Article
    Paraplégico mexe pernas após terapia com células-tronco

    Não se sabe se ele vai voltar a andar; paciente de 47 anos foi submetido a tratamento em fase experimental

    Pesquisadores na Bahia estão implantando células-tronco adultas em voluntários com lesão na medula

    GRACILIANO ROCHA
    DE SALVADOR

    Um paraplégico de 47 anos voltou a ter sensibilidade nas pernas e nos pés e a movimentar os membros inferiores após ser submetido a tratamento experimental * base de células-tronco, na Bahia.
    Desenvolvido por cientistas do Centro de Biotecnologia e Terapia Celular do Hospital São Rafael, em Salvador, e da Fiocruz, o tratamento consiste na retirada de células-tronco adultas do osso da bacia e no reimplante no local da lesão.
    O primeiro paciente, um policial militar de Salvador cuja identidade foi preservada, ficou paraplégico há nove anos, após uma queda que traumatizou a coluna na região lombar.
    Seis semanas após a implantação de células-tronco adultas no local da lesão, o paciente já voltou a sentir as pernas e os pés.
    Ele iniciou fisioterapia para fortalecer os músculos que ficaram muito atrofiados após o longo per*odo de inatividade.
    A bióloga Milena Soares, que participa do projeto, é cautelosa ao prever se o paciente voltará a andar um dia.
    Segundo ela, isso vai depender, sobretudo, da fisioterapia. "Ele já consegue fazer alguns movimentos com a perna, e os resultados já mostram avanços muito significativos para a qualidade de vida do paciente", diz.
    Os pesquisadores afirmam que houve um aumento do controle da bexiga e do esf*ncter. Com isso, o paciente ficará livre de cateterismos diários feitos para retirar urina.
    "Houve uma resposta muito boa no pós-operatório. Quatro dias depois [da cirurgia], o paciente já demonstrou melhora", diz Marcus Vin*cius Mendonça, neurocirurgião que integra o grupo.
    Nessa fase experimental, que visa atestar a segurança do procedimento, a técnica será aplicada em 20 voluntários. Dois deles receberam as células anteontem e ontem. O próximo fará o procedimento na semana que vem.
    Segundo Mendonça, caracter*sticas do pós-operatório verificadas no primeiro paciente, como ausência de dores neuropáticas (caracter*stica de lesões neurológicas), se repetiram nos outros dois pacientes.

  2. #2
    Interesting.
    "It's not the despair, I can handle the despair! It's the hope!" - John Cleese

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  3. #3
    Senior Member 0xSquidy's Avatar
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    In the portuguese article they say the improvements started 4 days post surgery. I don't think the cells themselves are that fast...
    Don't ask what clinical trials can do for you, ask what you can do for clinical trials.

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    Senior Member KIM's Avatar
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    Think that lesions are not homogeneous so there might be areas were the gap might be small and faster to reconect.

  5. #5
    It seems too good to be true... time will tell.
    I think the hospital is a serious one as it is part of an international network led by an italian one the "S. Raffaele Hospital" of Milan that is really a good one here.
    In God we trust; all others bring data. - Edwards Deming

  6. #6
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    Let us wait and see more patients being treated.

    Lumbar injury patients being recovered that is great news.

  7. #7
    the group envolved is 100% serious.

  8. #8
    I also saw this article/video. Unfortunately this is in portuguese too....

    http://g1.globo.com/bahia/noticia/20...-na-bahia.html

    Arcy

  9. #9
    Another legitimate clinical trial to add to the list it seems.

    At least this time it is not intravenous or intrathecal administration of bone marrow stem cells which has been done to death. It would be interesting to find out more about their transplant techniques.

  10. #10
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    Dear Fly Pelican this looks encouraging to us specially lower injuries whom need neuronal replacement therapy. I remember Dr Wise said in a thread that mesenchymal stem cells can be used for neuronal replacement.

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