ChinaSCINet Update

[tumbleweeds]

Jim, Wise has said that though the patients in Phase II could walk with CPG they couldn't lift their legs up from a lying position. Do you know if any of them could negotiate stairs/steps, pedal an exercise bike or swim?
Thanks

[lunasicc42]

Jim, is Wise back in America, if not; when does he get back and about when is the next official clinical update from chinascinet

[#LHB#]

Jim, is Wise back in America, if not; when does he get back and about when is the next official clinical update from chinascinet

Yea I would love to hear from Dr. Wise. I'm very interested to hear if the paper was submitted.

[Jim]

Jim, Wise has said that though the patients in Phase II could walk with CPG they couldn't lift their legs up from a lying position. Do you know if any of them could negotiate stairs/steps, pedal an exercise bike or swim?
Thanks

None were able to climb stairs, not sure about now.

Not sure if/when subjects from ChinaSCINet will be examined again. I know raising money to do this has been been discussed, but Wise has been incredibly busy setting up these trials in 3 countries.

[lunasicc42]

Jim, I can be pretty forgetful so I apologize if I have already asked this but will the possible improvements in bowel, bladder and sexual function be reported on in the next publication

[Jim]

No need to apologize luna.

There is no next publication from the ChinaSCINet IIa/b Clinical Trials. The next paper to come out will be on Lithium for Neuropathic Pain- http://www.chinascinet.org/index.php...146&Itemid=129 This trial has been completed and will be published soon. Lithium is very effective eliminating severe neuropathic pain. Not much of an effect on moderate pain.

The next step is approval of the Phase IIb trial here in the US, India, and Taiwan.

[lunasicc42]

No need to apologize luna.

There is no next publication from the ChinaSCINet IIa/b Clinical Trials. The next paper to come out will be on Lithium for Neuropathic Pain- http://www.chinascinet.org/index.php...146&Itemid=129 This trial has been completed and will be published soon. Lithium is very effective eliminating severe neuropathic pain. Not much of an effect on moderate pain.

The next step is approval of the Phase IIb trial here in the US, India, and Taiwan.

OK the exact wording of my question was incorrect but the 'meat' of my question still remains; "Will possible improvements or changes in Bowel, bladder and sexual function be analyzed and put in the publication of...in the near-future"

[FellowHawkeye]

Jim, I sometimes use lithium orotate tablets for anxiety, but never thought they'd help with the slight neuropathic pain in my left toes. I used to use gabapentin for that, but it affected my walking ability and now I use a pain cream. Do you know anything about lithium orotate? Thanks!-Jan

[Jim]

OK the exact wording of my question was incorrect but the 'meat' of my question still remains; "Will possible improvements or changes in Bowel, bladder and sexual function be analyzed and put in the publication of...in the near-future"

I don't know if/when the patients will be reexamined. They fulfilled their agreement by being examined at 6 months, 12, and 24. Another examination would yield very important information, I hope they do it. Unfortunately, Wise has no time to organize this.

Jim, I sometimes use lithium orotate tablets for anxiety, but never thought they'd help with the slight neuropathic pain in my left toes. I used to use gabapentin for that, but it affected my walking ability and now I use a pain cream. Do you know anything about lithium orotate? Thanks!-Jan

It is an incredible finding that a six week course of lithium greatly reduced/eliminated neuropathic pain, long term. There is much to learn.
I see that orotate is available over-the-counter, so it's properties are probably much different.

[lunasicc42]

I don't know if/when the patients will be reexamined. They fulfilled their agreement by being examined at 6 months, 12, and 24. Another examination would yield very important information, I hope they do it. Unfortunately, Wise has no time to organize this.



It is an incredible finding that a six week course of lithium greatly reduced/eliminated neuropathic pain, long term. There is much to learn.
I see that orotate is available over-the-counter, so it's properties are probably much different.

Naw, not the phase that is happening in china currently, I meant in the future usa trials, are possible changes in bbs going to to be looked at and documented then