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Thread: Bucking the Status Quo is Step One to the CURE

  1. #1

    Bucking the Status Quo is Step One to the CURE

    After 13 1/2 years with a totally blocked basilar artery, Jason received a balloon angio-plasty and a wingspan stent.

    As most of you know Jason has been paralyzed from the nose down ( incomplete locked-in) and the procedure that was done is described well over here:

    Since the FDA Humanitarian Device Exemption (HDE) approval of the Wingspan intracranial stent in August 2005,23 several publications have emerged in the literature reporting immediate periprocedural complication rates of 4.5–6.2% and re-stenosis rates of between 7% and 30% at 6 months.24 25 26 27 28 Two of the series also reported on clinical outcomes followed-up to 6 months, with combined rates of periprocedural stroke and death and ipsilateral stroke after 30 days of 7–14%.25 28 Currently, there are no published post-approval data on the long term clinical follow-up (greater than 6 months) after Wingspan stent placement. The aim of this study was to obtain preliminary data on the long term clinical and imaging outcomes of patients treated with the Wingspan stent for symptomatic intracranial arterial stenosis.
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    Institutional review board (IRB) approval was obtained for the HDE protocol and for clinical and imaging data collection, performed in accordance with the Health Insurance Portability and Accountability Privacy Act.
    http://jnis.bmj.com/content/1/1/40.full

    This will serve as step one for any stem cell treatment of the future, because as you know............no blood supply, no viable tissue..... stem cell or otherwise that can be administered.

    The IRB for Jason's procedure was obtained for one year at a Las Vegas Hospital. Jason was just 7 years old when he collided with another soccer player and became quadriplegic from a subsequent vertebral/basilar artery dissection.

    He is now 20 years old and has been a very strong stem cell research advocate, appearing on stage with Michael J. Fox:

    http://www.sptimes.com/2004/09/29/St...out_on_s.shtml

    Interventional radiologists have been at odds with neurosurgeons, and unfortunately stent placement remains under-utilized.

    Jason has a much easier time rolling over in bed, and I'm sure there is much more to come, with or without stem cell research!!!

    Faye
    Last edited by Pro-SCNT; 08-03-2010 at 04:49 PM.

  2. #2
    Quote Originally Posted by Pro-SCNT View Post
    Jason has a much easier time rolling over in bed, and I'm sure there is much more to come, with or without stem cell research!!!

    Faye
    To clarify the difference:

    It used to take him about 15 minutes to roll over in bed at night,.......now it only takes about 2 minutes.

    That constitutes major improvement, not barely measurable improvement that has been reported from "pharmaceuticals" like 4AP ( now Ampyra), which btw Jason tried early on within the first year of injury.
    Last edited by Pro-SCNT; 08-04-2010 at 06:56 PM.

  3. #3

    More on the Wingspan stent

    FOR IMMEDIATE RELEASE: December 20, 2005
    Contact: Sharon Boston sboston@umm.edu
    Ellen Beth Levitt eblevitt@umm.edu 410-328-8919
    UNIVERSITY OF MARYLAND DOCTORS USE NEW SELF-EXPANDING STENT TO OPEN CLOGGED ARTERIES IN THE BRAIN

    Maryland Forklift Operator is First Patient in the Mid-Atlantic Region to Receive Device
    The Wingspan Stent opens clogged arteries in the brain to allow blood to flow through.
    Doctors at the University of Maryland Medical Center are among the first in the nation to use a new, potentially life-saving stent to open clogged arteries in the brain. If left untreated, such blockages can lead to a stroke. The new device, called the Wingspan Stent System, is specifically designed to treat blockages in the brain caused by intracranial atherosclerotic disease, a condition that causes strokes in approximately 60,000 Americans each year. Physicians use a minimally invasive technique to deploy the stent inside the brain.
    "Stents have been used for many years to clear blockages in the arteries of the heart and neck. But the arteries in the brain present a very different challenge because they are more fragile and have many more curves, making it harder to get the stent to the site of the blockage," explains Abraham Obuchowski, M.D., the interventional neuroradiologist who performed the procedure at the University of Maryland Medical Center.

    John Dietz of Pasadena, Maryland, is the first patient in the mid-Atlantic region to receive Boston Scientific’s new Wingspan Stent, which recently received Food and Drug Administration approval for use through a humanitarian device exemption. The 46-year-old forklift operator had a stroke in October 2005, following a smaller stroke (transient ischemic attack) in July. Doctors then discovered that one of the arteries in Mr. Dietz’s brain was nearly three-quarters blocked, with just over half of a millimeter of space for the blood to move through.

    To help patients who are not getting enough benefit from medication, doctors have tried using stents designed for the heart, but these devices were stiff and difficult to maneuver in the brain. They are also made of steel, which can injure the brain’s more fragile blood vessels. The Wingspan Stent is made of nitinol, an alloy of nickel and titanium, which puts less pressure on the blood vessel when it expands.
    For the procedure, interventional neuroradiologists insert a catheter into an artery in the upper leg. Using digital X-rays for image guidance, the physicians navigate the catheter through the blood vessels to the site of the blockage in the brain. They then slowly inflate an angioplasty balloon to push away the plaque/clot and deploy the stent to hold the vessel open.
    http://www.umm.edu/news/releases/self_expand_stent.htm

    Jason will be getting his CTA neck ( CT angiogram of the neck) scan soon to evaluate patency of the basilar artery at 3 months post procedure. Can't wait to find out the results!!
    Since his blockage was due to a basilar artery dissection/clot rather than plaque, he shouldn't have any re-occlusion as he continues to take Plavix ( generic clopidigrel I ordered from Australia) and aspirin.

    Just to show you the sick state of our healthcare system:

    I paid over $200 for 30 Plavix pills in the US
    I paid just $29 for 60 clopidigrel from Australia

    Sick, sick rip-off system in the US!!
    Last edited by Pro-SCNT; 09-27-2010 at 03:37 PM.

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