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Thread: On Your Last Nerve: NC State Researchers Advance Understanding of Stem Cells

  1. #1

    On Your Last Nerve: NC State Researchers Advance Understanding of Stem Cells

    On Your Last Nerve: NC State Researchers Advance Understanding of Stem Cells
    Triangle


    Researchers from North Carolina State University have identified a gene that tells embryonic stem cells in the brain when to stop producing nerve cells called neurons. The research is a significant advance in understanding the development of the nervous system, which is essential to addressing conditions such as Parkinson’s disease, Alzheimer’s disease and other neurological disorders.

    The bulk of neuron production in the central nervous system takes place before birth, and comes to a halt by birth. But scientists have identified specific regions in the core of the brain that retain stem cells into adulthood and continue to produce new neurons.

    NC State researchers, investigating the subventricular zone, one of the regions that retains stem cells, have identified a gene that acts as a switch - transforming some embryonic stem cells into adult cells that can no longer produce new neurons. The research was done using mice. These cells form a layer of cells that support adult stem cells. The gene, called FoxJ1, increases its activity near the time of birth, when neural development slows down. However, the FoxJ1 gene is not activated in most of the stem cells in the subventricular zone - where new neurons continue to be produced into adulthood.


    more....

    http://www.sanjose.dbusinessnews.com...type_news=past

  2. #2
    Pushing the Brain to Find New Pathways


    ScienceDaily (Nov. 19, 2009) — Until recently, scientists believed that, following a stroke, a patient had about six months to regain any lost function. After that, patients would be forced to compensate for the lost function by focusing on their remaining abilities. Although this belief has been refuted, a University of Missouri occupational therapy professor believes that the current health system is still not giving patients enough time to recover and underestimating what the human brain can do given the right conditions.

    In a recent article for OT Practice Magazine, Guy McCormack, clinical professor and chair of the occupational therapy and occupational science department at the MU School of Health Professions, argues that health practitioners believe their clients need more time and motivation to reclaim lost functions, such as the use of an arm, hand or leg. With today's therapies, it is possible for patients to regain more function than ever thought possible, McCormack said.

    read....

    http://www.sciencedaily.com/releases...1117161118.htm

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