I cannot beleive the difference this has made. Before my botox injections I had a bladder that never cooperated. I was on multiple medications, ditropan xl , imipramine, desmopression, and several others. Non of which stopped my continual leaking and lack of capacity. Even with all the medications my bladder would start to spasm at 250-300cc's. I could never sleep throught the night and was up several times to cath. Since my injections on April 2 , 2009, exactly 6 yrs since my accident, I have been taken off all but my enablex, have not leaked, and am able to sleep through the night. I can not tell what it is like to have never slept through one night for six years!! I cant beleive it took so long to have this procedure recommended and done. It has certainly lightened the load for me. I would recommend this to anyone who has had continuing problems with neurogenic bladder. Now it is to see how long it will last. Urologist says 6-12 months, so I am 4 months out and doing well. I must say, the 30-40 injections were not that pleseant at times but has been well worth the pros of less meds, less cathing, and more sleep!!