There have been studies done, that with intense locomotive training the central pattern generator kicks in, which allows the person to walk, turn and stop, without a change in their lower extremities score. The people in these studies also cannot voluntarily move their legs lying down. I wonder how much of this research by Wise is kick starting the CPG due to intense rehab and nothing to do with the medication. I think we will see a clear sign of this in the US study since they will have one group with just rehab.