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Thread: $1 million to fund first 12 patient treatments /NEW Zealand!!!

  1. #11
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    Quote Originally Posted by Isildur View Post
    Huang? Lima? Reis?....Dr.Young?.... others?

    Do you have any information about the treatments they will test?
    Not yet, waiting for more press releases to come out. Previous info showed research focused on adult stem cells.
    The important thing in life is to have great aim, and the determination to attain it.

  2. #12
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    Nose cells may heal spine

    http://www.stuff.co.nz/stuff/4767623a7144.html

    Nose cells may heal spine

    By RUTH HILL - The Dominion Post | Friday, 21 November 2008

    People paralysed by spinal cord injuries could soon be "repaired" using cells from their own noses, say Otago University researchers.

    The Health Ministry's ethics committee has just approved an application by the Spinal Cord Society to open the way for a clinical trial involving 12 patients, which could start next year.

    The society's president, Noela Vallis, said there was no shortage of volunteers ready to take part.

    "Some have already gone overseas out of a sense of frustration that they can't access it [the experimental treatment] here," Mrs Vallis said.

    About 5000 Kiwis are in wheelchairs as a result of accidents - the highest rate of any country in the developed world.

    Research director Jim Faed, who heads the the Spinal Cord Society's lab at Otago University, has spent five years developing laboratory methods for growing cells potentially useful for spinal cord injury repair.

    His team is focusing on two promising cell types: one is a kind of adult stem cell produced by a patient's own bone marrow.

    However, researchers are likely to begin trials using olfactory (scent receptor) cells from the patient's nose, injecting them into damaged spinal cord.

    "The olfactory tissue in the nose is unique because it is the only place in the body where there is constant replacement of nerve cells throughout life," Dr Faed said.

    "There is growing medical opinion that these cells can help overcome the blocks that prevent nerve cells regenerating after damage to the spinal cord."

    The nasal tissue acts like "nurse cells", providing growth factor hormone to nerve cells, enabling them to make "meaningful connections".

    Internationally, several research groups have done animal trials using the cells, but there has been only one human trial - in Portugal in 2006. The Otago group is in contact with Portuguese neuropathologist Carlos Lima, who pioneered that trial.

    Dr Faed said some participants experienced side-effects, but they were "few and manageable" and none had been fatal.

    Positive benefits for patients included return of some muscle function and sensation in parts of the body which previously had no feeling.

    Dr Faed said the Dunedin lab hoped to get full approval for the trial before Christmas, and would then begin recruiting patients. The first 12 could start treatment next year.

    Mrs Vallis - who founded the society after her late husband was paralysed in an accident - said the group aimed to raise $1 million to fund the trial, in addition to the $300,000 it finds every year to run the lab. "We should be at the forefront of developing this medical treatment, given the number of our citizens in wheelchairs."

    More.

  3. #13
    I had hoped that the trials had a different approach than Lima..

  4. #14
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    Quote Originally Posted by topperf View Post
    I had hoped that the trials had a different approach than Lima..
    Yes, but so fare the only study done on humans has been a small ‘safety’ study by Lima. So then, maybe this bigger Kiwi study might be useful to conclude some more by others.

  5. #15
    True. I wish them the best, but have a hunch that this ain't enough to truly rock the boat.. But who knows - I'll keep everything crossed.

  6. #16
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    Let’s see. This at least will be carried out under strict trial control. It’s also a study on human chronic SCI as I can see. And as we know there is about zero of that in the world. And regardless the outcome maybe this in itself could set focus and put SCI research on the agenda in more countries urging for more SCI research and clinical trials. Just hoping they are not cutting out chunks of the cord at the injury site like Lima surgeons has done. But then again if they don’t create a ‘new’ injury site I’m not sure how these cells are supposed to work if at all.

  7. #17
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    Yeah it's for chronics. I believe they're starting with complete 't' level sci's then moving onto 'c' levels. Plus I thought SCS US had done rat studies previous using oec - but I could be wrong.
    The important thing in life is to have great aim, and the determination to attain it.

  8. #18
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    Quote Originally Posted by klj View Post
    Yeah it's for chronics. I believe they're starting with complete 't' level sci's then moving onto 'c' levels. Plus I thought SCS US had done rat studies previous using oec - but I could be wrong.
    Thanks for the info. Seems reasonable they test on t-levels first, less ‘complicated’ network and/thus easier to prove effects. And there have been some OEC studies on rats. Just search PubMed here; http://www.ncbi.nlm.nih.gov/sites/entrez/

    Please inform more as the trial picks up speed.

  9. #19

  10. #20
    Lima trial didn't work alot of ppl had it done and know one got any better that i've ever talk to in fact most lost function and yet he still doing the same things .

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