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Thread: Survival Of Diabetic Mice Improved After Transplantation Of Human Embryonic Stem Cell

  1. #1

    Survival Of Diabetic Mice Improved After Transplantation Of Human Embryonic Stem Cell

    Survival Of Diabetic Mice Improved After Transplantation Of Human Embryonic Stem Cell Derived ILCs
    Main Category: Diabetes
    Also Included In: Stem Cell Research
    Article Date: 29 Oct 2008 - 9:00 PDT

    Geron Corporation (Nasdaq:GERN) today announced the publication of data showing the successful engraftment of human embryonic stem cell (hESC)-derived pancreatic islet-like clusters (ILCs) in diabetic mice. After transplantation, the ILCs continued to express important pancreatic islet proteins, responded to high levels of glucose in the blood, and extended the survival of recipient animals.

    Pancreatic islet cells normally secrete insulin in response to high levels of glucose in the blood to maintain steady levels. Type 1 diabetes is an autoimmune disease in which the insulin secreting islet cells are destroyed. Administering insulin is life-saving but does not truly mimic the body's natural response to blood glucose and can result in serious complications such as diabetic retinopathy, nephropathy and neuropathy.

    more...

    http://www.medicalnewstoday.com/articles/127373.php

  2. #2
    Wednesday, Oct. 29, 2008

    Geron Corporation to Present at 7th Annual Bio Investor Forum


    MENLO PARK, Calif. — Geron Corporation (Nasdaq:GERN) today announced that Thomas B. Okarma, Ph.D., M.D., president and chief executive officer, will present an update of the company's product development programs at 9:00 a.m. PDT on Thursday, October 30, 2008, at the 7th Annual BIO Investor Forum in San Francisco.

    The update will include information about Geron's portfolio of anti-cancer therapies, including its telomerase inhibitor drug (GRN163L) and its telomerase therapeutic vaccine (GRNVAC1). The presentation will also include a review of the company's human embryonic stem cell (hESC) development programs for spinal cord injury (GRNOPC1), heart disease (GRNCM1) and diabetes (GRNIC1).

    more...

    http://www.centredaily.com/business/...ry/929917.html

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