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Type: Posts; User: LukeTheDuke

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  1. I believe, that Aspirin and Eliquiss inhibit both...

    I believe, that Aspirin and Eliquiss inhibit both different targets. And maybe it is not the blood clotting that needs to be inhibited. Potentially thrombin acts in other pathways as well ... just...
  2. Please be careful taking it; it might lead to...

    Please be careful taking it; it might lead to bleeding if you take too much
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    Was Rolipram or any other phosphodiesterase...

    Was Rolipram or any other phosphodiesterase inhibitor tested for SCI in humans? And if not, do you know why not?
  4. And would Pregabalin work equally well?

    And would Pregabalin work equally well?
  5. Please share: Wings for Life - World Run

    Please motivate as many people possible to join the World Run organized by Wings for Life

    Link:
    https://www.wingsforlifeworldrun.com/en/index.html



    All entry fees got to 100% into SCI...
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    Gabapentin vs Pregabalin

    What are your experiences regarding Gabapentin vs Pregabalin?

    Is there a clearly better one among those two?
    Who do you recommend to take which one under which circumstances?
    Do they have...
  7. Is there any researcher who tried combining...

    Is there any researcher who tried combining different types of stem cells? Any contraindication for giving all these cells people are talking about at the same time?
  8. Interesting read - thanks! Would that work...

    Interesting read - thanks!

    Would that work equally well for Gapapentin as it does for Pregabalin?

    Any opinion on which of those is better or worse?
  9. Understood. I think the entire trial, not for...

    Understood. I think the entire trial, not for each patient, takes 7 (2017-2023) though. And this is just phase I. Wondering how many years from now this could be approved and made available for the...
  10. Thanks for sharing. Does anyone know why this...

    Thanks for sharing.

    Does anyone know why this phase I trial takes 7 years? Are all stem cell trials taking this long? Do phase II and III also take 7 years each?
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    https://www.ncbi.nlm.nih.gov/pubmed/12151536 ...

    https://www.ncbi.nlm.nih.gov/pubmed/12151536
    https://www.ncbi.nlm.nih.gov/pubmed/12598630
    https://www.ncbi.nlm.nih.gov/pubmed/16624299


    I am not sure it works on chronic SCI though
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    Eusol and Kringle Pharma

    To the best of my knowledge Eusol and Kriingle Pharma have not received much attention here -- would like to get your perspective on the advancements of these two companies; have you heard of them?...
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    Gene therapy is a wide field with many...

    Gene therapy is a wide field with many opportunities. Imagine cells that

    express ChABC
    are "immune" to its own suppressors like Nogo, MAG OMgp
    express a higher amount of growth factors
    or...
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    I would start with the following papers: ...

    I would start with the following papers:

    https://www.ncbi.nlm.nih.gov/pubmed/12151536
    https://www.ncbi.nlm.nih.gov/pubmed/12598630
    https://www.ncbi.nlm.nih.gov/pubmed/16624299


    Not sure...
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    Thanks, Paolo! I agree that the halt of the...

    Thanks, Paolo!

    I agree that the halt of the Cethrin trial in phase IIb could indicate that Rock (Rho kinase) inhibitors might not work neither. However, Cethrin is a (derivative of a) bacterial...
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    Rock inhibitors in SCI

    Why are there no clinical trials with Rock inhibitors in SCI?

    There are plenty of Rock inhibitors and some are/ were in clinical trials for other indications

    ...
  17. Couple of questions: 1) What about the people...

    Couple of questions:

    1) What about the people with an injury below T11? Will you look into it? Will clinical trials start for such an injury as well? Can the central pattern generator be...
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