View Full Version : First African-American Genome Scan for Disease Genes

10-09-2006, 05:49 PM
SANTA CLARA, Calif.--(BUSINESS WIRE)--Affymetrix Inc. (Nasdaq:AFFX) announced today that researchers from Boston University and Howard University will perform the first genome-wide scan of an African American cohort searching for genes associated with obesity, hypertension, diabetes and metabolic syndrome using the Affymetrix GeneChip® Human Mapping 500K Array Set.

This collaborative study will be an important first step in understanding how genetics contribute to the disease burden of populations of African ancestry. Charles Rotimi, Ph.D., director of the National Human Genome Center at Howard University and current president of the African Society of Human Genetics, and Michael Christman, Ph.D., chair of the Genetics and Genomics Department at Boston University, will lead the study. The initial phase of the project will take less than a year and the team is hoping to secure additional funding to expand the study to include additional unique African cohorts.

To watch a full Affymetrix UserForum interview with Dr. Christman on this study, please visit http://www.affymetrix.com/userForum/news/collaborations/ChristmanVideo .uf (http://www.affymetrix.com/userForum/news/collaborations/ChristmanVideo.uf) (Due to its length, this URL may need to be copied/pasted into your Internet browser's address field. Remove the extra space if one exists.)

Dr. Rotimi’s team has conducted a number of family-based cohort studies on African populations. His areas of focus have been diabetes, obesity, hypertension and translational research.

“African Americans tend to have a higher frequency of obesity, diabetes, hypertension and metabolic syndrome than European Americans,” said Dr. Rotimi. “Through this first study, we hope to determine the genes associated with these complex diseases and discover how they may interact with different environmental factors, so we can develop more effective treatments for all Americans and people around the world.”

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