View Full Version : Stem Cells May Avert Amputation

07-19-2006, 05:30 AM
Using a patient's own stem cells, Indiana University doctors are pioneering a new way to prevent amputations in people with severe peripheral arterial disease. Known as PAD, it is a vascular disorder that affects the blood circulation in the feet, legs, kidney, stomach and arms.

In the only study of its kind in the United States, the researchers harvest adult stem cells from the patient's bone marrow and inject them into the diseased leg to prompt the development of new blood vessels and correct the problem.

Scientists believe that in healthy patients, stem cells from the bone marrow migrate out to repair organs and arteries when they get injured. Stem cells in people with PAD cannot reach the legs in sufficient numbers to make a difference.

So IU doctors decided to try transporting those potentially healing stem cells from the marrow to the leg for patients with advanced PAD.

Although only 10 patients to date have gone through the procedure, the results so far look promising, the researchers say.

"The information that we're getting from this study is telling us this therapy does indeed work, and we're learning more and more about how to isolate this information," said Dr. Michael Murphy, an assistant professor of surgery at Indiana University School of Medicine and the principal investigator of the trial.


07-31-2006, 05:53 PM
interesting research, that treatment could be used to treat a lot of conditions.

07-31-2006, 05:58 PM
I saw this as well ... wonder if it would work in a situation like mine with non-healing wounds on the feet.