View Full Version : ALS Association funds possible ALS treatment

03-15-2006, 03:38 PM
03/15/06 -- The ALS Association (ALSA) announced funding for a safety study in monkeys of an antisense drug to lower production of a mutant protein linked to some inherited cases of amyotrophic lateral sclerosis (ALS, also called Lou Gehrig's disease).

The investigators will contract with an outside facility to study 20 rhesus monkeys who will receive the antisense candidate delivered into the fluid surrounding the spinal cord (cerebrospinal fluid or CSF). The study will use the same equipment appropriate for human use. Delivery directly into the CSF is also the approach the investigators envision for human trials.