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roshni
02-18-2006, 11:37 AM
Protein level predicts who will develop deadly complication after marrow transplant

February 17, 2006

Inflammation marker measured at 1 week tied to 1-year survival rate
Researchers could determine one week after a bone marrow transplant which patients were likely to develop a serious and deadly complication, making them candidates for preventive treatment before any symptoms occur.

Researchers at the University of Michigan Comprehensive Cancer Center measured the level of a protein called tumor necrosis factor, or TNF, seven days after patients received a bone marrow transplant. TNF, a trigger for inflammation, is known to be elevated in people who develop graft vs. host disease, the most common serious side effect of a bone marrow transplant from a donor.

more on link: http://www.brightsurf.com/news/headlines/view.article.php?ArticleID=23131