Seifert, et al. (2005). Relapsing acute transverse myelitis: a specific entity.

[Wise Young]

The authors argue that relapsing transverse myelitis is a specific syndrome.

Seifert T, Enzinger C, Ropele S, Storch MK, Strasser-Fuchs S and Fazekas F (2005). Relapsing acute transverse myelitis: a specific entity. Eur J Neurol 12: 681-4. Acute transverse myelitis (ATM) not related to systemic disease may present in a relapsing manner. Data in the literature about this condition are scarce. We describe three patients suffering from relapsing myelitis in whom no association with systemic disease, i.e. infectious or connective tissue disease was found. Magnetic resonance imaging (MRI) findings were also distinctly different from multiple sclerosis and consistent with a necrotizing type of inflammation. Despite various treatment strategies, all patients became severely disabled. Relapsing ATM not related to systemic disease appears to be a specific entity which accounts for severe disability and currently lacks effective treatment. Department of Neurology, Graz Medical University, Graz, Austria. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16128868

[Sue Pendleton]

This is the weird kind of stuff I've been trying to catch up on. During the TM Symposium in 2001 I heard about recurring (A)TM, spinal MS, optic neuritis, Devic's?, and ADEM besides the just slightly weird strokes, PPS, regular one time TM, etc.

[Steven Edwards]

Sue,

A new study (http://www.eurekalert.org/pub_releases/2005-09/joci-acn091505.php) was released by Doug Kerr that showed levels of the IL-6 cytokine are signifigantly higher in the CSF of idiopathic TM patients than in control subjects. They further went on to show that IL-6 alone is sufficient to induce paralysis.

Not a bad find, overall.

...and, welcome back. :)

[lynnifer]

Thank you so much for posting this. Always looking for answers as to what happened to cause my TM.

[anty]

thank you for that info on TM. i think i know how i got TM. but thats another story, anty :thinking: