Wise Young
05-14-2002, 06:18 PM
Schwid SR, Goodman AD, McDermott MP, Bever CF and Cook SD (2002). Quantitative functional measures in MS: what is a reliable change? Neurology. 58 (8): 1294-6. Summary: As a first step toward understanding which changes should be considered as meaningful, the authors assessed the reliability of quantitative functional tests on 5 consecutive days in 63 patients with MS, determining the range of measurement variability present when patients are clinically stable. Time to walk 25 feet (T25FW) and the 9-hole peg test (9HPT) varied by <20% of individual mean scores on repeated testing. Therefore, a 20% change on these tests can be considered to be the threshold that reliably indicates a true change in function for an individual. Department of Neurology, University of Rochester Medical Center, NY, USA. Steven_Schwid@urmc.rochester.edu