Wise Young
10-01-2001, 05:04 PM
http://www.nature.com/cgi-taf/DynaPage.taf?file=/nrn/journal/v2/n10/full/nrn1001-745a_fs.html
Nature Reviews Neuroscience 2, 745 -749 (2001)
Interventional strategies against prion
diseases
Adriano Aguzzi, Markus Glatzel, Fabio Montrasio, Marco Prinz &
Frank L. Heppner
Preface
Only a few years ago, the idea that transmissible spongiform
encephalopathies could be treated pharmacologically would have met
with considerable scepticism. Even now, there is no way to cure a
patient or animal suffering from a manifest prion disease. But recent,
exciting developments seem to indicate that immunological and
pharmacological interventions could have some potential for the
pre-exposure and post-exposure prophylaxis of prion diseases.
Although it is unlikely that we will be able to cure the clinically overt
stages of prion diseases in the foreseeable future, palliative and even
life-prolonging interventions might no longer be confined to the realm
of science fiction.
Nature Reviews Neuroscience 2, 745 -749 (2001)
Interventional strategies against prion
diseases
Adriano Aguzzi, Markus Glatzel, Fabio Montrasio, Marco Prinz &
Frank L. Heppner
Preface
Only a few years ago, the idea that transmissible spongiform
encephalopathies could be treated pharmacologically would have met
with considerable scepticism. Even now, there is no way to cure a
patient or animal suffering from a manifest prion disease. But recent,
exciting developments seem to indicate that immunological and
pharmacological interventions could have some potential for the
pre-exposure and post-exposure prophylaxis of prion diseases.
Although it is unlikely that we will be able to cure the clinically overt
stages of prion diseases in the foreseeable future, palliative and even
life-prolonging interventions might no longer be confined to the realm
of science fiction.