Max
12-17-2001, 04:42 PM
Level of injury and hormone profiles in spinal cord-injured men [In Process Citation]
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Urology 2001 Nov;58(5):671-6 (ISSN: 1527-9995)
Safarinejad MR [Find other articles with this Author]
Department of Urology, Division of Urology and Renal Transplantation, Military University of Medical Sciences, Air Force Hospital, Tehran, Iran.
Objectives. To evaluate the level of injury and endocrine profiles in men with spinal cord injury (SCI).Methods. Seventy-six men with SCI at different levels were studied, using uninjured normal and infertile subjects as controls.Results. Compared with normal controls, the subjects with SCI (50%) had lower serum levels of luteinizing hormone, follicle-stimulating hormone, and testosterone. Subjects with T8-T11 and T12-L5 injury had the highest and lowest incidence of hormonal abnormalities, respectively. All subjects with hyperprolactinemia (n = 5) had T8-T11 injuries.Conclusions. The results of our study indicate that subjects with SCI have an altered central neurotransmitter tone, and the likelihood of these abnormalities (hypogonadotropism) are higher in men with low thoracic SCI.
Language: English
MEDLINE Indexing Date: 200111
Publication Type: Journal Article
PreMedline Identifier: 0011711334
Unique NLM Identifier: 21568860
Journal Code: IM
Selected
Urology 2001 Nov;58(5):671-6 (ISSN: 1527-9995)
Safarinejad MR [Find other articles with this Author]
Department of Urology, Division of Urology and Renal Transplantation, Military University of Medical Sciences, Air Force Hospital, Tehran, Iran.
Objectives. To evaluate the level of injury and endocrine profiles in men with spinal cord injury (SCI).Methods. Seventy-six men with SCI at different levels were studied, using uninjured normal and infertile subjects as controls.Results. Compared with normal controls, the subjects with SCI (50%) had lower serum levels of luteinizing hormone, follicle-stimulating hormone, and testosterone. Subjects with T8-T11 and T12-L5 injury had the highest and lowest incidence of hormonal abnormalities, respectively. All subjects with hyperprolactinemia (n = 5) had T8-T11 injuries.Conclusions. The results of our study indicate that subjects with SCI have an altered central neurotransmitter tone, and the likelihood of these abnormalities (hypogonadotropism) are higher in men with low thoracic SCI.
Language: English
MEDLINE Indexing Date: 200111
Publication Type: Journal Article
PreMedline Identifier: 0011711334
Unique NLM Identifier: 21568860
Journal Code: IM